Renee Wegrzyn, PhD, Director of the Advanced Research Projects Agency for Health (ARPA-H), announced funding of three new programs to support the Cancer Moonshot during a hosted by POLITICO. :
• Targeted Hybrid Oncotherapeutic Regulation (THOR): $45 million to Rice University to develop a minimally invasive implant that senses and responds with a specific treatment and will trigger the immune system against tumors.
• Synthetic Programmable bacteria for Immune-directed Killing in tumor Environments (SPIKEs): Up to $19 million to the University of Missouri to develop an inexpensive and safe therapy using bacteria specifically selected for tumor-targeting.
• Cancer and Organ Degradome Atlas (CODA): Up to $50 million to the Georgia Institute of Technology to map cancer cell biomarkers to drastically improve multi-cancer early detection and streamline clinical intervention when tumors are still small.
Danielle Carnival, PhD, Deputy Assistant to the President for the Cancer Moonshot, reiterated the collaboration and non-duplicative efforts among ARPA-H and the National Cancer Institute during the update. She also emphasized the relationship between innovative technology and access to care, emphasizing preventive care and early detection.
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